Just as with the developer and publishing sector of the video games industry, iGaming (casino and betting) is incredibly competitive at the developer level. Huge software companies, many with a global presence, vie for the attention of players and hope that their games are picked up by the best online casinos.

There are similarities to the iGaming software and video games industries in the sense that iGaming brands, such as Microgaming or Playtech, are held in the same regard with casino players as brands like Capcom and Blizzard might be with gamers. Individual games, too, can become smash hits.

But perhaps the one difference is that it can be difficult to get reliable data. It’s not easy to find out what is the most played online casino game in 2021. But we do have some information to work on, not least what games are promoted by individual casinos and what titles are talked about in social media.

Indeed, you could argue that each of the top developers has a ‘signature game’ in the same way that Nintendo might have Super Mario or Rockstar has Grand Theft Auto. Below we list those signature titles from each of the world’s best iGaming developers.

Playtech – Buffalo Blitz

A good gauge of a casino game’s popularity is whether it is popular enough to get a sequel. That’s certainly the case here. At casino.com you can play Buffalo Blitz and Buffalo Blitz II, both of which are hugely popular titles. Moreover, Playtech chose this game as the launch game for its live slots experience – a communal live slot game that you play with a dealer.

Microgaming – Mega Moolah

Microgaming is widely considered to be the first creator of online casino software, although these things are often disputed in the wild west days of the internet in the 1990s. As such, the company has produced over 1,000 titles in its time. As for the signature game, though, it has to be Mega Moolah – the game that entered Guinness World records for having the biggest

NetEnt – Starburst

We flirted with the idea of putting Gonzo’s Quest on this list as it is another massively popular game, but Starburst gets the nod – it might just be the most played online casino game on the planet. It features prominently on the best casino sites, as well as bingo platforms. A very simple game, NetEnt caught lightning in a bottle with its funky design – and we are astounded that the company has not released a sequel.

IGT – Cleopatra

If you were to take a flight to Las Vegas, you would see rows of Wheel of Fortune slots the moment you disembark from the plane and enter McCarran Airport. IGT made its name with physical slot machines, but it is also a big player online. And, arguably, the mystical Cleopatra slot outshines Wheel of Fortune in the online market. It’s a classic.

Blueprint – Ted

The first branded game on this list, Ted is based on the Seth Macfarlane movie. It features incredible 3D graphics, and it is just as fun – and risqué – as the source material. Aside from the movie references, there are lots of Ted-themed bonus games and special features. Great stuff from Blueprint.

Big Time Gaming – Bonanza

The game that started the Megaways revolution – a new style of slot that offers over 100,000 ways to win in each spin. Bonanza is a simple mining themed casino game, but it caught the imagination of players with its unique Megaways format. Right now, there are around 200 Megaways titles – but the original is always worth playing.

Play n’ Go – Book of Dead

Arguably the slot that vies with Starburst as being the world’s most popular title, Book of Dead is a fun adventure-themed game that has shades of Lara Croft and Indiana Jones. To be frank, it can be a bit boring in the base game – but everyone loves the free spins feature with expanding symbols.

Push Gaming – Jammin’ Jars

A unique game that is beloved of streamers playing casino games on sites like YouTube and Twitch, Jammin’ Jars looks cute but offers huge payouts on occasion. And, that makes for wild entertainment.

Pragmatic Play – Sweet Bonanza

Our final game on this list is one of Pragmatic’s most popular titles – Sweet Bonanza. Like Jammin’ Jars above, it looks cute. But that belies some serious payout potential for players. This game is probably more popular in North America than Europe, but its candy theme is recognisable anywhere.